February 10, 2009

Dead Silence and a Thud (Day 5/6 Report)

The dead silence part is my mouth hanging open, the thud is my jaw hitting the ground.

Of our 29 embryos, 22 made it to Day 5. They were able to biopsy 13 yesterday, which is 60%. For comparison's sake, last time they were able to biopsy 6 of 18 on Day 5, or 33%.

Last time, they grew out 12 more to Day 6, and wound up biopsying 4, or 25%. This time, there were 9 they weren't able to biopsy yesterday that they grew to today. Of those, they were able to biopsy 8, or 89%.

Overall, they biopsied 21 of the 22 that made it to the blast stage. (Insert dead silence, thud here.) Apparently, we've set a record for the most number of blasts biopsied from one retrieval. This batch is being sent out for micro-array rather than CGH, so that hopefully we won't get as high a percentage of "no results" this time around.

Both the embryologist I spoke with yesterday and the one I spoke with today gushed about how amazingly perfect our embryos look - they said there wasn't one average-graded one in the bunch. I swear, I think they were doing a little happy dance on our behalf.

But then I mentioned to today's embryologist that I've noticed from other patients that the embryos that are graded the best tend to be the abnormal ones, and she said, "Yeah, a lot of the ones that we would recommend transferring based on how they look come back abnormal. We've been very surprised by that." So basically, she agreed with me - after telling me that all of ours look fabulous.

Then she went on to add, "Down's Syndrome embryos in particular make beautiful blasts. They tend to look great on Day 5!" Gee, that really helps, thanks.

I know, I know. I should be very grateful. And I am. And I keep telling myself that this was a different protocol, so hopefully it will have a different (better) outcome.

But I have to admit, the biggest part of me is still afraid that I'm going to get a phone call in two months telling me that we have 21 absolutely beautiful, totally abnormal blasts.

13 comments:

Sue said...

Okay, that is flat-out incredible! I have heard that sometimes the best looking embies aren't the healthiest...but you are so far ahead of the curve on this one! I am now upping my bet to say that I'm sure that you will get a good number of healthy embryos - though I know, you can't help worrying that you won't even get one normal (that is what this miserable IF teaches us - glass half empty thinking! I'd be thinking the same way). BUT, I think with that many, you will find out that you have good ones in there. I can't count how many times on the boards I've seen women get pregnant with 4AA blasts - and those are the prettiest out there! Hang in there! Congrats! the more the merrier (now, don't go putting 6 back in:-P - sorry, was watching the Today show and getting ticked off at that mom of 14 and how it is going to influence how many I can transfer in a few months).

DAVs said...

Well, super congrats on getting so many to even be tested! I'm sorry the embryologists went on to say weird stuff about looks and abnormals, but maybe you'll set a new record in that way, too! I seriously can't imagine that ALL of them are abnormal. As someone who's never even made one single solitary blast, making that many just seems unbelievable to me!
I hope the wait zings by!

Fashionably Infertile said...

That is fantastic news! I know you have a long road ahead but you at least are going into the process with better odds! Congratulations!!!

kayjay said...

OMG that is such a high number of blasts that were biopsied! I know you want to hold off on the happy dance given your other post about if only looks mattered but there just has to be a few normals in there. There just has to be. I will cross my fingers and toes for you and wish you a speedy wait time. GL!!

MamaSoon said...

I can totally see where you'd be reserved. But the numbers are on your side. And all it takes is ONE normal. I hope you get a surprise and get 10 normals or something amazing!

Thalia said...

I have to think that with 21 biopsied, the numbers are on your side, there must be one normal one in there, at least. Congratulations!

Nic said...

With that number to biopsy, I have to imagine there will be at least ONE healthy embryo in there. And hopefully lots more! You're going to do one more round of retrieval, right? Will you wait until you get the results of this before you go again, or not?

Anniep said...

Awesome numbers! Hey, 90% could still be crap, but at this point you have quantity on your side... my fingers are crossed for ya in the quality dept.

I wonder if the micro-array lab is totally different from the CGH lab...

Polly Gamwich said...

Holy cow ... that is ... amazing! I seriously can't imagine that you could be in a better position. I SO HOPE that you don't find them all to be abnormal - that would be so unlikely I would think?

Wow, I can't imagine how these next 8 weeks will be for you.

At least you get to start them on a high.

GL!!!!

Grad3 said...

I am happy for you and praying loudly that you have 4 great embryos for transfer :)

I nominated you on my blog because you are fabulous! Hugs

Polly Gamwich said...

Just checking in on you. Only been 2w, but wanting to make sure all is well.

Linda said...

Ok, so I'm super late in commenting, but wow girlie! 21 blasts biopsied! When we went back in November, we only had 15 and THAT was the record. I'm so glad that you were able to beat that record! :) I hope you get great results soon! I'm so excited for you!

tintedsky said...

i hope you will have great news!